Salt‐sensitive hypertension is associated with reduced urea transporter B expression in the choroid plexus and increased Na + concentration in the cerebrospinal fluid
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منابع مشابه
Cerebrospinal fluid secretion by the choroid plexus.
The choroid plexus epithelium is a cuboidal cell monolayer, which produces the majority of the cerebrospinal fluid. The concerted action of a variety of integral membrane proteins mediates the transepithelial movement of solutes and water across the epithelium. Secretion by the choroid plexus is characterized by an extremely high rate and by the unusual cellular polarization of well-known epith...
متن کاملChronic lead exposure alters transthyretin concentration in rat cerebrospinal fluid: the role of the choroid plexus.
The choroid plexus, which is responsible for the maintenance of the biochemical milieu of the cerebrospinal fluid (CSF), avidly sequesters Pb. In order to test the hypothesis that chronic Pb exposure may impair choroid plexus function, male weanling Sprague-Dawley rats were exposed to Pb in drinking water at doses of 0, 50, or 250 micrograms Pb/ml (as Pb acetate) for 30, 60, or 90 days. The fun...
متن کاملThe choroid plexus removes beta-amyloid from brain cerebrospinal fluid.
beta-Amyloid (Abeta) concentration in the cerebrospinal fluid (CSF) of the brain may be regulated by the choroid plexus, which forms a barrier between blood and brain CSF. Abeta uptake from CSF was determined as its volume of distribution (V(D)) into isolated rat choroid plexus tissue. The V(D) of [125I]Abeta1-40 was corrected by subtraction of the V(D) of [14C]sucrose, a marker for extracellul...
متن کاملSecretion of Cerebrospinal Fluid by Choroid Plexus of the Rabbit.
WELCH, KEASLEY. Secretion uf cerebrospinal jluid by choroid plexus of the rabbit. Am. J. Physiol. 205(3): 617-624 1963.Blood flow in the principal draining vein of the choroid plexus of the lateral ventricle of the rabbit, which drains approximately the anterior 70% of the plexus, was measured by the analysis of motion pictures made during the injection of spheruler of r-octanol. The relative l...
متن کاملThe choroid plexus-cerebrospinal fluid system: from development to aging.
The function of the cerebrospinal fluid (CSF) and the tissue that secretes it, the choroid plexus (CP), has traditionally been thought of as both providing physical protection to the brain through buoyancy and facilitating the removal of brain metabolites through the bulk drainage of CSF. More recent studies suggest, however, that the CP-CSF system plays a much more active role in the developme...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2015
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.29.1_supplement.623.2